The gut microbiota regulates autism-like behavior by mediating vitamin B6 homeostasis in EphB6-deficient mice

The gut microbiota regulates autism-like behavior by mediating vitamin B6 homeostasis in EphB6-deficient mice

Abstract Background Autism spectrum disorder (ASD) is a developmental disorder, and the effective pharmacological treatments for the core autistic symptoms are currently limited. Increasing evidence, particularly that from clinical studies on ASD patients, suggests a functional link between the gut...

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Main Authors: Ying Li, Zheng-Yi Luo, Yu-Ying Hu, Yue-Wei Bi, Jian-Ming Yang, Wen-Jun Zou, Yun-Long Song, Shi Li, Tong Shen, Shu-Ji Li, Lang Huang, Ai-Jun Zhou, Tian-Ming Gao, Jian-Ming Li
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Microbiome
Subjects:
Gut microbiota
ASD
EphB6
Vitamin B6
Dopamine
E/I balance
Online Access:http://link.springer.com/article/10.1186/s40168-020-00884-z

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http://link.springer.com/article/10.1186/s40168-020-00884-z

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