Visualization of Tau–Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique

Visualization of Tau–Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique

Tau is a neuron-specific microtubule-binding protein that stabilizes microtubules. It is generally thought that highly phosphorylated tau dissociates from microtubules and becomes insoluble aggregates, leading to neuronal degeneration. Due to the implication of tau aggregation in neurodegenerative d...

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Bibliographic Details
Main Authors: Seulgi Shin, Sungsu Lim, Hyeanjeong Jeong, Li Ting Kwan, Yun Kyung Kim
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
tau aggregation
microtubule
tubulin
Bifluorescence Complementation
neurodegeneration
Online Access:http://www.mdpi.com/1422-0067/19/10/2978

Internet

http://www.mdpi.com/1422-0067/19/10/2978

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