Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state.

In contrast to mammals, lower vertebrates are capable of extraordinary myocardial regeneration thanks to the ability of their cardiomyocytes to undergo transient dedifferentiation and proliferation. Somatic cells can be temporarily reprogrammed to a proliferative, dedifferentiated state through forc...

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Bibliographic Details
Main Authors: Thomas Kisby, Irene de Lázaro, Maria Stylianou, Giulio Cossu, Kostas Kostarelos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0251054