The Epithelial to Mesenchymal Transition Promotes Glutamine Independence by Suppressing <i>GLS2</i> Expression

The Epithelial to Mesenchymal Transition Promotes Glutamine Independence by Suppressing <i>GLS2</i> Expression

Identifying bioenergetics that facilitate the epithelial to mesenchymal transition (EMT) in breast cancer cells may uncover targets to treat incurable metastatic disease. Metastasis is the number one cause of cancer-related deaths; therefore, it is urgent to identify new treatment strategies to prev...

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Bibliographic Details
Main Authors: Esmeralda Ramirez-Peña, James Arnold, Vinita Shivakumar, Robiya Joseph, Geraldine Vidhya Vijay, Petra den Hollander, Neeraja Bhangre, Paul Allegakoen, Rishika Prasad, Zachary Conley, José M. Matés, Javier Márquez, Jeffrey T. Chang, Suhas Vasaikar, Rama Soundararajan, Arun Sreekumar, Sendurai A. Mani
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
<i>gls2</i>
emt
glutamine metabolism
breast cancer
<i>foxc2</i>
Online Access:https://www.mdpi.com/2072-6694/11/10/1610

Internet

https://www.mdpi.com/2072-6694/11/10/1610

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