A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women[S]

A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women[S]

While conventional pharmacogenetic studies have considered single gene effects, we tested if a genetic score of nine LDL- and HDL-associated single nucleotide polymorphisms, previously shown to predict cardiovascular disease, is related to fluvastatin-induced lipid change. In patients with asymptoma...

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Bibliographic Details
Main Authors: Viktor Hamrefors, Marju Orho-Melander, Ronald M. Krauss, Bo Hedblad, Peter Almgren, Göran Berglund, Olle Melander
Format: Article
Language:English
Published: Elsevier 2010-03-01
Series:Journal of Lipid Research
Subjects:
genetic score
statins
pharmacogenetics
atherosclerosis
carotid plaque
lipid levels
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520305204

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http://www.sciencedirect.com/science/article/pii/S0022227520305204

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