Intermittent Hypoxia Activates Duration-Dependent Protective and Injurious Mechanisms in Mouse Lung Endothelial Cells

Intermittent Hypoxia Activates Duration-Dependent Protective and Injurious Mechanisms in Mouse Lung Endothelial Cells

Intermittent hypoxia is a major factor in clinical conditions like the obstructive sleep apnea syndrome or the cyclic recruitment and derecruitment of atelectasis in acute respiratory distress syndrome and positive pressure mechanical ventilation. In vivo investigations of the direct impact of inter...

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Bibliographic Details
Main Authors: Peter Wohlrab, Lourdes Soto-Gonzales, Thomas Benesch, Max Paul Winter, Irene Marthe Lang, Klaus Markstaller, Verena Tretter, Klaus Ulrich Klein
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Physiology
Subjects:
lung endothelium
intermittent hypoxia
obstructive sleep apnea
alternating oxygen conditions
atelectasis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01754/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01754/full

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