MGMT-Methylation in Non-Neoplastic Diseases of the Central Nervous System

MGMT-Methylation in Non-Neoplastic Diseases of the Central Nervous System

Quantifying O<sup>6</sup>-methylguanine-DNA methyltransferase (MGMT) promoter methylation plays an essential role in assessing the potential efficacy of alkylating agents in the chemotherapy of malignant gliomas. MGMT promoter methylation is considered to be a characteristic of subgroups...

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Bibliographic Details
Main Authors: Sarah Teuber-Hanselmann, Karl Worm, Nicole Macha, Andreas Junker
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
DNA-methylation
MGMT promoter methylation
multiple sclerosis
progressive multifocal leucencephalopathy (PML)
central pontine and exptrapontine myelinolysis
Wallerian degeneration
Online Access:https://www.mdpi.com/1422-0067/22/8/3845

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https://www.mdpi.com/1422-0067/22/8/3845

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