Evaluation of alignment algorithms for discovery and identification of pathogens using RNA-Seq.

Next-generation sequencing technologies provide an unparallelled opportunity for the characterization and discovery of known and novel viruses. Because viruses are known to have the highest mutation rates when compared to eukaryotic and bacterial organisms, we assess the extent to which eleven well-...

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Bibliographic Details
Main Authors: Ivan Borozan, Stuart N Watt, Vincent Ferretti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3813700?pdf=render