GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.

GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.

Non-Hodgkin lymphoma (NHL) represents a diverse group of hematological malignancies, of which follicular lymphoma (FL) is a prevalent subtype. A previous genome-wide association study has established a marker, rs10484561 in the human leukocyte antigen (HLA) class II region on 6p21.32 associated with...

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Main Authors: Karin E Smedby, Jia Nee Foo, Christine F Skibola, Hatef Darabi, Lucia Conde, Henrik Hjalgrim, Vikrant Kumar, Ellen T Chang, Nathaniel Rothman, James R Cerhan, Angela R Brooks-Wilson, Emil Rehnberg, Ishak D Irwan, Lars P Ryder, Peter N Brown, Paige M Bracci, Luz Agana, Jacques Riby, Wendy Cozen, Scott Davis, Patricia Hartge, Lindsay M Morton, Richard K Severson, Sophia S Wang, Susan L Slager, Zachary S Fredericksen, Anne J Novak, Neil E Kay, Thomas M Habermann, Bruce Armstrong, Anne Kricker, Sam Milliken, Mark P Purdue, Claire M Vajdic, Peter Boyle, Qing Lan, Shelia H Zahm, Yawei Zhang, Tongzhang Zheng, Stephen Leach, John J Spinelli, Martyn T Smith, Stephen J Chanock, Leonid Padyukov, Lars Alfredsson, Lars Klareskog, Bengt Glimelius, Mads Melbye, Edison T Liu, Hans-Olov Adami, Keith Humphreys, Jianjun Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3080853?pdf=render

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http://europepmc.org/articles/PMC3080853?pdf=render

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