Breed-specific expression of GR exon 1 mRNA variants and profile of GR promoter CpG methylation in the hippocampus of newborn piglets

Breed-specific expression of GR exon 1 mRNA variants and profile of GR promoter CpG methylation in the hippocampus of newborn piglets

Glucocorticoid receptor (GR) transcription is driven by alternative promoters to produce different exon 1 mRNA variants. CpG methylation on GR promoters profoundly affects GR transcription. GR in hippocampus is critical for energy homeostasis and stress responses, yet it remains unclear whether hipp...

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Bibliographic Details
Main Authors: Q. Sun, Y. Jia, R. Li, X. Li, X. Yang, R. Zhao
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Animal
Subjects:
glucocorticoid receptor
hippocampus
methylation
pig
variant
Online Access:http://www.sciencedirect.com/science/article/pii/S1751731114001700

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http://www.sciencedirect.com/science/article/pii/S1751731114001700

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