Monocytes/Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma

Monocytes/Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma

We recently identified CXCR4 as a novel vascular marker for vessel sprouting in hepatocellular carcinoma (HCC) tissues. Thus, CXCR4+ endothelial cells (ECs) could serve as a potential predictor for patients who may benefit from sorafenib treatment; however, the mechanism that regulates vascular CXCR...

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Bibliographic Details
Main Authors: Ya-Ming Meng, Jing Liang, Chong Wu, Jing Xu, Dan-Ni Zeng, Xing-Juan Yu, Huiheng Ning, Li Xu, Limin Zheng
Format: Article
Language:English
Published: Taylor & Francis Group 2018-03-01
Series:OncoImmunology
Subjects:
cxcr4
tumor endothelial cell
monocyte/macrophage
tnf-α
hcc
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1408745

Internet

http://dx.doi.org/10.1080/2162402X.2017.1408745

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