Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging

Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging

The accumulation of lipids, including cholesterol, in the arterial wall plays a key role in the pathogenesis of atherosclerosis. Although several advances have been made in the detection and imaging of these lipid structures in plaque lesions, their morphology and composition have yet to be fully el...

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Bibliographic Details
Main Authors: Ryan S. Lim, Jeffrey L. Suhalim, Shinobu Miyazaki-Anzai, Makoto Miyazaki, Moshe Levi, Eric O. Potma, Bruce J. Tromberg
Format: Article
Language:English
Published: Elsevier 2011-12-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
LDL receptor
ApoE
hyperspectral coherent anti-Stokes Raman scattering
nonlinear optical microscopy
principal component analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408223

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http://www.sciencedirect.com/science/article/pii/S0022227520408223

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