HCV genomic RNA activates the NLRP3 inflammasome in human myeloid cells.

HCV genomic RNA activates the NLRP3 inflammasome in human myeloid cells.

Elevated plasma levels of IL-1β and IL-18 from patients with hepatitis C virus (HCV) infection indicate a possible activation of inflammasome by HCV.To demonstrate whether HCV infection activates the inflammasome, we investigated inflammasome activation from HCV infected hepatic Huh7 cells, or monoc...

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Bibliographic Details
Main Authors: Wei Chen, Yongfen Xu, Hua Li, Wanyin Tao, Yu Xiang, Bing Huang, Junqi Niu, Jin Zhong, Guangxun Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882267?pdf=render

Internet

http://europepmc.org/articles/PMC3882267?pdf=render

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