A randomized approach to speed up the analysis of large-scale read-count data in the application of CNV detection

A randomized approach to speed up the analysis of large-scale read-count data in the application of CNV detection

Abstract Background The application of high-throughput sequencing in a broad range of quantitative genomic assays (e.g., DNA-seq, ChIP-seq) has created a high demand for the analysis of large-scale read-count data. Typically, the genome is divided into tiling windows and windowed read-count data is...

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Bibliographic Details
Main Authors: WeiBo Wang, Wei Sun, Wei Wang, Jin Szatkiewicz
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Bioinformatics
Subjects:
Bioinformatic
Computational biology
Next-generation sequencing
Online Access:http://link.springer.com/article/10.1186/s12859-018-2077-6

Internet

http://link.springer.com/article/10.1186/s12859-018-2077-6

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