Positive regulation of DNA double strand break repair activity during differentiation of long life span cells: the example of adipogenesis.

Little information is available on the ability of terminally differentiated cells to efficiently repair DNA double strand breaks (DSBs), and one might reasonably speculate that efficient DNA repair of these threatening DNA lesions, is needed in cells of long life span with no or limited regeneration...

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Bibliographic Details
Main Authors: Aline Meulle, Bernard Salles, Danièle Daviaud, Philippe Valet, Catherine Muller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2556389?pdf=render