Low Molecular Weight Dextran Sulfate (ILB<sup>®</sup>) Administration Restores Brain Energy Metabolism Following Severe Traumatic Brain Injury in the Rat

Low Molecular Weight Dextran Sulfate (ILB<sup>®</sup>) Administration Restores Brain Energy Metabolism Following Severe Traumatic Brain Injury in the Rat

Traumatic brain injury (TBI) is the leading cause of death and disability in people less than 40 years of age in Western countries. Currently, there are no satisfying pharmacological treatments for TBI patients. In this study, we subjected rats to severe TBI (sTBI), testing the effects of a single s...

Full description

Bibliographic Details
Main Authors: Giacomo Lazzarino, Angela Maria Amorini, Nicholas M. Barnes, Lars Bruce, Alvaro Mordente, Giuseppe Lazzarino, Valentina Di Pietro, Barbara Tavazzi, Antonio Belli, Ann Logan
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Antioxidants
Subjects:
severe traumatic brain injury
low molecular weight dextran sulfate
mitochondrial dysfunction
energy metabolism
<i>N</i>-acetylaspartate
nicotinic coenzymes
Online Access:https://www.mdpi.com/2076-3921/9/9/850

Internet

https://www.mdpi.com/2076-3921/9/9/850

Similar Items