Granulocyte Colony-Stimulating Factor Receptor mutations in myeloid malignancy

Granulocyte colony-stimulating factor (G-CSF) is a cytokine able to stimulate both myelopoiesis and hematopoietic stem cell mobilization, which has seen it used extensively in the clinic to aid hematopoietic recovery. It acts specifically via the homodimeric, granulocyte colony-stimulating factor re...

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Bibliographic Details
Main Authors: Clifford eLiongue, Alister Curtis Ward
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Oncology
Subjects:
AML
SCN
mds
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00093/full