The subcellular compartmentalization of arginine metabolizing enzymes and their role in endothelial dysfunction

The subcellular compartmentalization of arginine metabolizing enzymes and their role in endothelial dysfunction

The endothelial production of nitric oxide (NO) mediates endothelium-dependent vasorelaxation and restrains vascular inflammation, smooth muscle proliferation and platelet aggregation. Impaired production of NO is a hallmark of endothelial dysfunction and promotes the development of cardiovascular...

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Bibliographic Details
Main Authors: Feng eChen, Rudolph eLucas, David eFulton
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Arginase
eNOS
L-arginine
nitric
CAT-1
ASL
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00184/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00184/full

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