Expression, Covariation, and Genetic Regulation of miRNA Biogenesis Genes in Brain Supports their Role in Addiction, Psychiatric Disorders, and Disease

Expression, Covariation, and Genetic Regulation of miRNA Biogenesis Genes in Brain Supports their Role in Addiction, Psychiatric Disorders, and Disease

The role of miRNA and miRNA biogenesis genes in the adult brain is just beginning to be explored. In this study we have performed a comprehensive analysis of the expression, genetic regulation, and co-expression of major components of the miRNA biogenesis pathway using human and mouse data sets and...

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Bibliographic Details
Main Authors: Megan Kathleen Mulligan, Candice eDuBose, Junming eYue, Michael F. Miles, Lu eLu, Kristin M Hamre
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Genetics
Subjects:
Brain
Gene Expression Regulation
Addiction
miRNA
BXD
behavioral phenotype
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00126/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00126/full

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