HIV-neutralizing activity of cationic polypeptides in cervicovaginal secretions of women in HIV-serodiscordant relationships.

HIV exposed seronegative (HESN) women represent the population most in need of a prophylactic antiviral strategy. Mucosal cationic polypeptides can potentially be regulated for this purpose and we here aimed to determine their endogenous expression and HIV neutralizing activity in genital secretions...

Full description

Bibliographic Details
Main Authors: Pauline Levinson, Robert Y Choi, Amy L Cole, Taha Hirbod, Samuel Rhedin, Barbara Payne, Brandon L Guthrie, Rose Bosire, Alexander M Cole, Carey Farquhar, Kristina Broliden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3289637?pdf=render