Role of Matrix Metalloproteinase-8 in Atherosclerosis

Plaque rupture is the main cause of acute myocardial infarction and stroke. Atherosclerotic plaques have been described to be vulnerable and more prone to rupture when they are characterized by thin, highly inflamed, and collagen-poor fibrous caps and contain elevated levels of proteases, including...

Full description

Bibliographic Details
Main Authors: Sébastien Lenglet, François Mach, Fabrizio Montecucco
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/659282