Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury

Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury

The neuroinflammatory response to traumatic brain injury (TBI) is critical to both neurotoxicity and neuroprotection, and has been proposed as a potentially modifiable driver of secondary injury in animal and human studies. Attempts to broadly target immune activation have been unsuccessful in impro...

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Bibliographic Details
Main Authors: Saef Izzy, Qiong Liu, Zhou Fang, Sevda Lule, Limin Wu, Joon Yong Chung, Aliyah Sarro-Schwartz, Alexander Brown-Whalen, Caroline Perner, Suzanne E. Hickman, David L. Kaplan, Nikolaos A. Patsopoulos, Joseph El Khoury, Michael J. Whalen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
traumatic brain injury
microglia
transcriptome
neurodegeneration
mice
neuroimmunology
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00307/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00307/full

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