Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Abstract Background Current heart failure (HF) treatment is based on targeting symptoms and left ventricle dysfunction severity, relying on a common HF pathway paradigm to justify common treatments for HF patients. This common strategy may belie an incomplete understanding of heterogeneous underlyin...

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Bibliographic Details
Main Authors: Mary E. Sweet, Andrea Cocciolo, Dobromir Slavov, Kenneth L. Jones, Joseph R. Sweet, Sharon L. Graw, T. Brett Reece, Amrut V. Ambardekar, Michael R. Bristow, Luisa Mestroni, Matthew R. G. Taylor
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Genomics
Subjects:
RNA-seq
Transcriptome
Gene expression
Cardiomyopathy
Heart failure
Online Access:http://link.springer.com/article/10.1186/s12864-018-5213-9

Internet

http://link.springer.com/article/10.1186/s12864-018-5213-9

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