Palladium-catalyzed allene synthesis enabled by β-hydrogen elimination from sp 2 -carbon
β-Hydrogen elimination is a fundamental reaction in palladium catalysis, however, the eliminated β-hydrogen is usually attached to a sp 3 -carbon. Here, the authors report a palladium-catalyzed cross-coupling reaction involving a β-vinylic hydrogen elimination from an allylic palladium intermediate....
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-20740-w |