Glomerular Collagen Deposition and Lipocalin-2 Expression Are Early Signs of Renal Injury in Prediabetic Obese Rats

Glomerular Collagen Deposition and Lipocalin-2 Expression Are Early Signs of Renal Injury in Prediabetic Obese Rats

Feeding rats with high-fat diet (HFD) with a single streptozotocin (STZ) injection induced obesity, slightly elevated fasting blood glucose and impaired glucose and insulin tolerance, and caused cardiac hypertrophy and mild diastolic dysfunction as published before by Koncsos et al. in 2016. Here we...

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Bibliographic Details
Main Authors: Eva Nora Bukosza, Tamás Kaucsár, Mária Godó, Enikő Lajtár, Pál Tod, Gábor Koncsos, Zoltán V. Varga, Tamás Baranyai, Minh Tu Nguyen, Helga Schachner, Csaba Sőti, Péter Ferdinandy, Zoltán Giricz, Gábor Szénási, Péter Hamar
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
obesity
renal injury
lipocalin-2
collagen type IV
inflammation
Online Access:https://www.mdpi.com/1422-0067/20/17/4266

Internet

https://www.mdpi.com/1422-0067/20/17/4266

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