Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories

Flexible fear-related responses may be advantageous in adolescence. Here the authors use microprisms to image prefrontal cortical spine maturation across development and report that plasticity in adolescent fear extinction responses is associated with dynamic reorganization in the amygdalahippocampa...

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Bibliographic Details
Main Authors: Siobhan S. Pattwell, Conor Liston, Deqiang Jing, Ipe Ninan, Rui R. Yang, Jonathan Witztum, Mitchell H. Murdock, Iva Dincheva, Kevin G. Bath, B. J. Casey, Karl Deisseroth, Francis S. Lee
Format: Article
Language:English
Published: Nature Publishing Group 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11475