In vitro HIV infection impairs the capacity of myeloid dendritic cells to induce regulatory T cells.

Myeloid dendritic cells (mDCs) are the antigen-presenting cells best capable of promoting peripheral induction of regulatory T cells (Tregs), and are among the first targets of HIV. It is thus important to understand whether HIV alters their capacity to promote Treg conversion. Monocyte-derived DCs...

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Bibliographic Details
Main Authors: Pietro Presicce, Maria E Moreno-Fernandez, Laura K Rusie, Carl Fichtenbaum, Claire A Chougnet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3418294?pdf=render