A Bilayer Vaginal Tablet for the Localized Delivery of Disulfiram and 5-Fluorouracil to the Cervix

A Bilayer Vaginal Tablet for the Localized Delivery of Disulfiram and 5-Fluorouracil to the Cervix

This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating cancerous cells in the margin of cervical tumors. The vaginal tablet is a ve...

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Bibliographic Details
Main Authors: Ismin Zainol Abidin, Emanuele Rezoagli, Bianca Simonassi-Paiva, Gustavo Waltzer Fehrenbach, Kevin Masterson, Robert Pogue, Zhi Cao, Neil Rowan, Emma J. Murphy, Ian Major
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Pharmaceutics
Subjects:
chitosan
polyacrylic acid
mucoadhesion
cervical cancer
vaginal drug delivery
bilayer tablets
Online Access:https://www.mdpi.com/1999-4923/12/12/1185

Internet

https://www.mdpi.com/1999-4923/12/12/1185

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