Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy

BackgroundImmune checkpoint therapies (ICTs) targeting the programmed cell death-1 (PD1)/programmed cell death ligand-1 (PD-L1) pathway have improved outcomes for patients with non-small cell lung cancer (NSCLC), particularly those with high PD-L1 expression. However, the predictive value of manual...

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Bibliographic Details
Main Authors: Andreas Spitzmüller, Thomas Herz, Marlon C. Rebelatto, Helene Kaplon, Brandon W. Higgs
Format: Article
Language:English
Published: BMJ Publishing Group 2019-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/7/1/121.full