Novel Potent and Selective DPP-4 Inhibitors: Design, Synthesis and Molecular Docking Study of Dihydropyrimidine Phthalimide Hybrids

<i>Background</i>: Dipeptidyl peptidase-4 (DPP-4) inhibitors have emerged as anti-hyperglycemic agents that improve glycemic control in type 2 diabetic patients, either as monotherapy or in combination with other antidiabetic drugs. <i>Methods</i>: A novel series of dihydropy...

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Bibliographic Details
Main Authors: Ahmed A. E. Mourad, Ahmed E. Khodir, Sameh Saber, Mai A. E. Mourad
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/2/144