Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.

Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.

Although paediatric high grade gliomas resemble their adult counterparts in many ways, there appear to be distinct clinical and biological differences. One important factor hampering the development of new targeted therapies is the relative lack of cell lines derived from childhood glioma patients,...

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Bibliographic Details
Main Authors: Dorine A Bax, Suzanne E Little, Nathalie Gaspar, Lara Perryman, Lynley Marshall, Marta Viana-Pereira, Tania A Jones, Richard D Williams, Anita Grigoriadis, Gilles Vassal, Paul Workman, Denise Sheer, Rui M Reis, Andrew D J Pearson, Darren Hargrave, Chris Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2666263?pdf=render

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http://europepmc.org/articles/PMC2666263?pdf=render

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