RNF219/α‐Catenin/LGALS3 Axis Promotes Hepatocellular Carcinoma Bone Metastasis and Associated Skeletal Complications

RNF219/α‐Catenin/LGALS3 Axis Promotes Hepatocellular Carcinoma Bone Metastasis and Associated Skeletal Complications

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Abstract The incidence of bone metastases in hepatocellular carcinoma (HCC) has increased prominently over the past decade owing to the prolonged overall survival of HCC patients. However, the mechanisms underlying HCC bone‐metastasis remain largely unknown. In the current study, HCC‐secreted lectin...

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Bibliographic Details
Main Authors: Shuxia Zhang, Yingru Xu, Chan Xie, Liangliang Ren, Geyan Wu, Meisongzhu Yang, Xingui Wu, Miaoling Tang, Yameng Hu, Ziwen Li, Ruyuan Yu, Xinyi Liao, Shuang Mo, Jueheng Wu, Mengfeng Li, Erwei Song, Yanfei Qi, Libing Song, Jun Li
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Advanced Science
Subjects:
bone metastasis
hepatocellular carcinoma
LGALS3
RNF219
skeletal‐related events
Online Access:https://doi.org/10.1002/advs.202001961

Internet

https://doi.org/10.1002/advs.202001961

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