Azithromycin treats diffuse panbronchiolitis by targeting T cells via inhibition of mTOR pathway

Azithromycin treats diffuse panbronchiolitis by targeting T cells via inhibition of mTOR pathway

Azithromycin (AZM), that is a macrolide antibiotic, has been found to treat diffuse panbronchiolitis (DPB) effectively. However, the mechanism of action underlying the therapeutic effects remains unclear. We selected 64 patients with DPB from 305 patients who were diagnosed with DPB at the outpatien...

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Bibliographic Details
Main Authors: Dong Weng, Qin Wu, Xian-Qiu Chen, Yu-Kui Du, Tao Chen, Hong Li, Dan-Li Tang, Qiu-Hong Li, Yuan Zhang, Li-Qin Lu, Nian-Yu Zhou, Jia-Cui Song, Chen Wang, Hui-Ping Li
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Azithromycin
CD4+ T cells
Diffuse panbronchiolitis
IL-17A
mTOR
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218355604

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http://www.sciencedirect.com/science/article/pii/S0753332218355604

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