Azobenzene-based inhibitors of human carbonic anhydrase II

Azobenzene-based inhibitors of human carbonic anhydrase II

Aryl sulfonamides are a widely used drug class for the inhibition of carbonic anhydrases. In the context of our program of photochromic pharmacophores we were interested in the exploration of azobenzene-containing sulfonamides to block the catalytic activity of human carbonic anhydrase II (hCAII). H...

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Bibliographic Details
Main Authors: Leander Simon Runtsch, David Michael Barber, Peter Mayer, Michael Groll, Dirk Trauner, Johannes Broichhagen
Format: Article
Language:English
Published: Beilstein-Institut 2015-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
azobenzene chemistry
enzyme inhibitors
human carbonic anhydrase II
sulfonamide
X-ray crystallography
Online Access:https://doi.org/10.3762/bjoc.11.127

Internet

https://doi.org/10.3762/bjoc.11.127

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