Zfp296 is a novel, pluripotent-specific reprogramming factor.

Zfp296 is a novel, pluripotent-specific reprogramming factor.

Expression of the four transcription factors Oct4, Sox2, Klf4, and c-Myc (OSKM) is sufficient to reprogram somatic cells into induced pluripotent stem (iPSCs). However, this process is slow and inefficient compared with the fusion of somatic cells with embryonic stem cells (ESCs), indicating that ES...

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Bibliographic Details
Main Authors: Gerrit Fischedick, Diana C Klein, Guangming Wu, Daniel Esch, Susanne Höing, Dong Wook Han, Peter Reinhardt, Kerstin Hergarten, Natalia Tapia, Hans R Schöler, Jared L Sterneckert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3317644?pdf=render

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http://europepmc.org/articles/PMC3317644?pdf=render

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