Reexamining microRNA site accessibility in Drosophila: a population genomics study.

Kertesz et al. (Nature Genetics 2008) described PITA, a miRNA target prediction algorithm based on hybridization energy and site accessibility. In this note, we used a population genomics approach to reexamine their data and found that the PITA algorithm had lower specificity than methods based on e...

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Bibliographic Details
Main Authors: Kevin Chen, Jonas Maaskola, Mark L Siegal, Nikolaus Rajewsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2682560?pdf=render