A secreted form of the asialoglycoprotein receptor, sH2a, as a novel potential noninvasive marker for liver fibrosis.

BACKGROUND AND AIM: The human asialoglycoprotein receptor is a membrane heterooligomer expressed exclusively in hepatocytes. A soluble secreted form, sH2a, arises, not by shedding at the cell surface, but by intracellular cleavage of its membrane-bound precursor, which is encoded by an alternatively...

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Bibliographic Details
Main Authors: Elena Veselkin, Maria Kondratyev, Yoav Lurie, Efrat Ron, Moshe Santo, Shimon Reif, Irma Elashvili, Lana Bar, Gerardo Z Lederkremer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3214029?pdf=render