Detecting the Effects of the Glucocorticoid Dexamethasone on Primary Human Skeletal Muscle Cells—Differences to the Murine Cell Line

Detecting the Effects of the Glucocorticoid Dexamethasone on Primary Human Skeletal Muscle Cells—Differences to the Murine Cell Line

Skeletal muscle atrophy is characterized by a decrease in muscle fiber size as a result of a decreased protein synthesis, which leads to degradation of contractile muscle fibers. It can occur after denervation and immobilization, and glucocorticoids (GCs) may also increase protein breakdown contribu...

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Bibliographic Details
Main Authors: Eva K. Langendorf, Pol M. Rommens, Philipp Drees, Stefan G. Mattyasovszky, Ulrike Ritz
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
atrophy
MuRF-1
myotubes
myoblasts
MAFbx
glucocorticoids
Online Access:https://www.mdpi.com/1422-0067/21/7/2497

Internet

https://www.mdpi.com/1422-0067/21/7/2497

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