Defining the binding region in factor H to develop a therapeutic factor H-Fc fusion protein against nontypeable Haemophilus influenzae

Nontypeable Haemophilus influenzae (NTHi) cause a range of illnesses including otitis media, sinusitis, and exacerbation of chronic obstructive pulmonary disease, infections that contribute to the problem of antibiotic resistance and are themselves often intractable to standard antibiotic treatment...

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Bibliographic Details
Main Authors: Sandy M. Wong, Jutamas eShaughnessy, Sanjay eRam, Brian J. Akerley
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
P5
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00040/full