Effects of Mefloquine Use on Plasmodium vivax Multidrug Resistance

Effects of Mefloquine Use on Plasmodium vivax Multidrug Resistance

Numerous studies have indicated a strong association between amplification of the multidrug resistance-1 gene and in vivo and in vitro mefloquine resistance of Plasmodium falciparum. Although falciparum infection usually is not treated with mefloquine, incorrect diagnosis, high frequency of undetect...

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Bibliographic Details
Main Authors: Nimol Khim, Voahangy Andrianaranjaka, Jean Popovici, Saorin Kim, Arsene Ratsimbasoa, Christophe Benedet, Celine Barnadas, Remy Durand, Marc Thellier, Eric Legrand, Lise Musset, Michela Menegon, Carlo Severini, Bakri Y.M. Nour, Magali Tichit, Christiane Bouchier, Odile Mercereau-Puijalon, Didier Ménard
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2014-10-01
Series:Emerging Infectious Diseases
Subjects:
Plasmodium vivax
drug resistance
mdr-1 gene
mefloquine
copy number
malaria
Online Access:https://wwwnc.cdc.gov/eid/article/20/10/14-0411_article

Internet

https://wwwnc.cdc.gov/eid/article/20/10/14-0411_article

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