Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'

<p>Abstract</p> <p>Background</p> <p>The frequency of a haplotype comprising one allele at each of two loci can be expressed as a cubic equation (the 'Hill equation'), the solution of which gives that frequency. Most haplotype and linkage disequilibrium analys...

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Bibliographic Details
Main Authors: Day Ian NM, Rodríguez Santiago, Gaunt Tom R
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/8/428