Immuno-therapy with anti-CTLA4 antibodies in tolerized and non-tolerized mouse tumor models.

Monoclonal antibodies specific for cytotoxic T lymphocyte-associated antigen 4 (anti-CTLA4) are a novel form of cancer immunotherapy. While preclinical studies in mouse tumor models have shown anti-tumor efficacy of anti-CTLA4 injection or expression, anti-CTLA4 treatment in patients with advanced c...

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Bibliographic Details
Main Authors: Jonas Persson, Ines Beyer, Roma Yumul, ZongYi Li, Hans-Peter Kiem, Steve Roffler, André Lieber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3136517?pdf=render