Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon

Abstract Schistosomiasis (bilharzia) is a neglected tropical disease caused by parasitic flatworms of the genus Schistosoma, with considerable morbidity in parts of the Middle East, South America, Southeast Asia, in sub-Saharan Africa, and particularly also in Europe. The WHO describes an increasing...

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Bibliographic Details
Main Authors: Jakob Weglage, Friederike Wolters, Laura Hehr, Jakob Lichtenberger, Celina Wulz, Felix Hempel, Anne Baier, Thomas Quack, Kernt Köhler, Thomas Longerich, Gabriele Schramm, Karuna Irungbam, Heike Mueller, Verena von Buelow, Annette Tschuschner, Margarete Odenthal, Uta Drebber, Maha El Arousy, Leandra N. Z. Ramalho, Katrin Bankov, Peter Wild, Jörn Pons-Kühnemann, Jonas Tschammer, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79450-4