Protective effect of ginsenoside Rb1 against tacrolimus-induced apoptosis in renal proximal tubular LLC-PK1 cells

Protective effect of ginsenoside Rb1 against tacrolimus-induced apoptosis in renal proximal tubular LLC-PK1 cells

Background: The aim of the present study was to evaluate the potential protective effects of six ginsenosides (Rb1, Rb2, Rc, Rd, Rg1, and Rg3) isolated from Panax ginseng against tacrolimus (FK506)-induced apoptosis in renal proximal tubular LLC-PK1 cells. Methods: LLC-PK1 cells were treated with FK...

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Bibliographic Details
Main Authors: Dahae Lee, Dong-Soo Lee, Kiwon Jung, Gwi Seo Hwang, Hye Lim Lee, Noriko Yamabe, Hae-Jeong Lee, Dae-Woon Eom, Ki Hyun Kim, Ki Sung Kang
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Ginseng Research
Subjects:
caspase-3
FK506-induced nephrotoxicity
ginsenoside Rb1
KIM-1
MAPKs
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845316301737

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http://www.sciencedirect.com/science/article/pii/S1226845316301737

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