The local complement activation on vascular bed of patients with systemic sclerosis: a hypothesis-generating study.

OBJECTIVE:The role of complement system in the pathogenesis of systemic sclerosis (SSc) has been debated during the last decade but an evident implication in this disease has never been found. We carried out an explorative study on SSc patients to evaluate the expression of soluble and local C5b-9 c...

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Main Authors: Cinzia Scambi, Sara Ugolini, T Sakari Jokiranta, Lucia De Franceschi, Oscar Bortolami, Valentina La Verde, Patrizia Guarini, Paola Caramaschi, Viviana Ravagnani, Guido Martignoni, Chiara Colato, Serena Pedron, Fabio Benedetti, Marco Sorio, Fabio Poli, Domenico Biasi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319765?pdf=render