High efficiency lipid-based siRNA transfection of adipocytes in suspension.

BACKGROUND:Fully differentiated adipocytes are considered to be refractory to introduction of siRNA via lipid-based transfection. However, large scale siRNA-based loss-of-function screening of adipocytes using either electroporation or virally-mediated transfection approaches can be prohibitively co...

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Bibliographic Details
Main Authors: Gail Kilroy, David H Burk, Z Elizabeth Floyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2736387?pdf=render