miR-146a-5p-mediated suppression on trophoblast cell progression and epithelial-mesenchymal transition in preeclampsia

miR-146a-5p-mediated suppression on trophoblast cell progression and epithelial-mesenchymal transition in preeclampsia

Abstract Objective This study aims to identify the effect of miR-146a-5p on trophoblast cell invasion as well as the mechanism in preeclampsia (PE). Methods Expression levels of miR-146a-5p and Wnt2 in preeclamptic and normal placentae were quantified. Trophoblast cells (HTR-8) were separately trans...

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Bibliographic Details
Main Authors: Pingping Peng, Huamei Song, Chenghong Xie, Wenfei Zheng, Huigai Ma, Dandan Xin, Jingqiong Zhan, Xiaoqing Yuan, Aihua Chen, Jing Tao, Jufang Qin
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Biological Research
Subjects:
Trophoblast cells
miR-146a-5p
Wnt2
Proliferation
Migration
Epithelial-mesenchymal transition
Online Access:https://doi.org/10.1186/s40659-021-00351-5

Internet

https://doi.org/10.1186/s40659-021-00351-5

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