Simvastatin inhibits planktonic cells and biofilms of Candida and Cryptococcus species

The antifungal activity of some statins against different fungal species has been reported. Thus, at the first moment, the in vitro antifungal activity of simvastatin, atorvastatin and pravastatin was tested against Candida spp. and Cryptococcus spp. Then, in a second approach, considering that the...

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Bibliographic Details
Main Authors: Raimunda Sâmia Nogueira Brilhante, Erica Pacheco Caetano, Jonathas Sales de Oliveira, Débora de Souza Collares Maia Castelo-Branco, Elizabeth Ribeiro Yokobatake Souza, Lucas Pereira de Alencar, Rossana de Aguiar Cordeiro, Tereza de Jesus Pinheiro Gomes Bandeira, José Júlio Costa Sidrim, Marcos Fábio Gadelha Rocha
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867015001038