Inhibition of glycogen phosphorylase stimulates ventromedial hypothalamic nucleus AMP‐activated protein kinase

Inhibition of glycogen phosphorylase stimulates ventromedial hypothalamic nucleus AMP‐activated protein kinase

Abstract The glucose polymer glycogen is a vital fuel reserve in the brain. The mediobasal hypothalamic energy sensor AMP‐activated protein kinase (AMPK) maintains glucostasis via neurotransmitter mechanisms that suppress [γ‐aminobutyric acid; GABA] or stimulate [nitric oxide; steroidogenic factor‐1...

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Bibliographic Details
Main Authors: Hussain N. Alhamami, Ayed Alshamrani, Karen P. Briski
Format: Article
Language:English
Published: Wiley 2017-12-01
Series:Physiological Reports
Subjects:
AMP‐activated protein kinase
glutamate decarboxylase
glycogen phosphorylase
insulin‐induced hypoglycemia
nitric oxide synthase
ventromedial hypothalamic nucleus
Online Access:https://doi.org/10.14814/phy2.13484

Internet

https://doi.org/10.14814/phy2.13484

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