Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells.

Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells.

The production of new blood cells relies on a hierarchical network of hematopoietic stem and progenitor cells (HSPCs). To maintain lifelong hematopoiesis, HSPCs must be protected from ionizing radiation or other cytotoxic agents. For many years, murine models have been a valuable source of informati...

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Bibliographic Details
Main Authors: Benjamin J Povinelli, Kathleen M Kokolus, Jason W-L Eng, Christopher W Dougher, Leslie Curtin, Maegan L Capitano, Christi T Sailsbury-Ruf, Elizabeth A Repasky, Michael J Nemeth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368554?pdf=render

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http://europepmc.org/articles/PMC4368554?pdf=render

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